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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
24.85
Human Site:
S576
Identified Species:
42.05
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
S576
S
S
V
I
S
D
D
S
V
L
S
S
D
S
F
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S576
S
S
V
I
S
D
D
S
V
L
S
S
D
S
F
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
S582
S
S
V
I
S
D
D
S
V
L
S
S
D
S
F
Dog
Lupus familis
XP_538417
666
74288
S581
S
S
V
I
S
D
D
S
V
L
S
S
D
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
S577
S
S
I
I
S
D
D
S
V
L
S
S
D
S
F
Rat
Rattus norvegicus
Q66HE5
630
69934
L555
A
V
S
E
D
S
I
L
S
S
E
S
F
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
S576
S
S
V
I
S
D
D
S
I
L
S
S
D
S
F
Chicken
Gallus gallus
Q9IA88
798
88848
F568
A
S
L
L
P
V
S
F
Q
E
G
R
R
A
S
Frog
Xenopus laevis
NP_001088596
570
64876
G495
F
E
L
L
D
F
P
G
K
Y
R
E
R
A
R
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
P898
T
P
L
E
Y
R
P
P
P
Q
V
T
P
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
I1199
K
S
P
R
E
F
I
I
P
I
A
V
E
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
S742
A
T
S
S
S
S
S
S
S
A
T
S
T
A
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
G436
M
K
C
R
W
V
P
G
L
A
D
G
Q
N
T
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
K555
W
K
Y
D
I
G
N
K
T
N
T
N
E
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
93.3
6.6
0
0
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
33.3
20
26.6
N.A.
26.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
0
0
0
0
0
0
15
8
0
0
22
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
15
43
43
0
0
0
8
0
43
8
0
% D
% Glu:
0
8
0
15
8
0
0
0
0
8
8
8
15
0
0
% E
% Phe:
8
0
0
0
0
15
0
8
0
0
0
0
8
0
43
% F
% Gly:
0
0
0
0
0
8
0
15
0
0
8
8
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
43
8
0
15
8
8
8
0
0
0
0
8
% I
% Lys:
8
15
0
0
0
0
0
8
8
0
0
0
0
8
0
% K
% Leu:
0
0
22
15
0
0
0
8
8
43
0
0
0
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
8
0
8
0
8
0
% N
% Pro:
0
8
8
0
8
0
22
8
15
0
0
0
8
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
0
0
8
0
8
% Q
% Arg:
0
0
0
15
0
8
0
0
0
0
8
8
15
0
8
% R
% Ser:
43
58
15
8
50
15
15
50
15
8
43
58
0
43
8
% S
% Thr:
8
8
0
0
0
0
0
0
8
0
15
8
8
8
8
% T
% Val:
0
8
36
0
0
15
0
0
36
0
8
8
0
0
0
% V
% Trp:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _